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Combination treatment

Combination treatment for methamphetamine use disorder shows promise in new study

A combination of two medications, injectable naltrexone and oral bupropion, was safe and effective in treating adults with moderate or severe methamphetamine use disorder in a double-blind, placebo-controlled Phase III clinical trial. The findings suggest this combination therapy may be a promising addition to current approaches to treatment, such as cognitive behavioral therapy and contingency…

A combination of two medications, injectable naltrexone and oral bupropion, was safe and effective in treating adults with severe or moderate methamphetamine use disorder in a double, placebo-controlled Phase III clinical trial. The findings suggest this combination therapy might be a promising addition to present approaches to treatment, such as cognitive behavioral treatment and contingency management interventions, for a very serious illness that remains hard to treat and conquer. The study, published today in The New England Journal of Medicine, has been conducted in multiple sites within the National Institute on Drug Abuse Clinical Trials Network (NIDA CTN). NIDA is part of the National Institutes of Health.
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